In-vitro evaluation of Mg-4.0Zn-0.2Ca alloy for biomedical application
(1. Stomatology Hospital, Harbin Medical University, Harbin 150001, China;
2. State Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150080, China)
2. State Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150080, China)
Abstract: The in-vitro degradation and in-vitro cytotoxicity of the as-extruded Mg-4.0Zn-0.2Ca alloy were investigated. The in-vitro corrosion tests indicate that Zn and Ca elements can dramatically increase the corrosion potential of the as-extruded Mg-4.0Zn-0.2Ca alloy in the simulated body fluid and reduce the degradation rate. The cytotoxicity of the as-extruded Mg-4.0Zn-0.2Ca alloy examined by MTT tests on L929 cells suggest that the alloy has eligible toxicity for implant applications.
Key words: magnesium alloy; biodegradation; biocompatibility; cytotoxicity