The microstructure and creep behavior of C/Y₂O₃ synergistically micro-alloyed high-Al and low-Al TiAl alloys prepared by induction skull melting (ISM) technology were investigated by advanced electron microscopy. Microstructure analysis shows that Y₂O₃ particles are dispersed in both alloys; element C is dissolved in low-Al alloys as solid solution, while it exists as Ti₂AlC particles within lamellae in high-Al alloys. Additionally, high-density nanotwins are generated in high-Al alloys. Creep data show that C/Y₂O₃ micro-alloying significantly enhances creep resistance of TiAl alloys. This benefits from the dispersion strengthening of Y₂O₃ particles, precipitation hardening of dynamically precipitated Ti₃AlC particles and lamellar stabilization caused by dissolved C atoms or Ti₂AlC particles. This strategy causes a more significant improvement on creep resistance of high-Al TiAl alloys, which is attributed to extra twin strengthening effect. At 775-850 °C, these alloys fracture in mixed ductile-brittle mode, but the fracture characteristics change with the increase of temperature.